The Special Crimes Unit is a branch of the police department which investigates crimes believed to be perpetrated by the paranormal and superhuman. There are only two such organizations in the country to overtly employ superhuman police as a single unit like this.
New York SCU
The NYPD SCU was the first in the nation, and the initial decision to depend heavily on outside contractors given peace officer status was very controversial. However, the squad's early success, especially that of the contractors, in preventing a metahuman gang war from developing in the power vacuum left by the collapse of Sanctuary in its first form convinced the public and the city government to keep them on. Its members and exploits are detailed in the Professionals storyline.
Los Santos SCU
Its methods have been considered extreme, and its presence controversial in nature. Detailed in Chapter 7 of the Heroes? campaign.